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Glucosamine

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Glucosamine Chondroitin Vitamin Shoppe Osteo Bi-Flex Glucosamine
Glucosamine | Osteo Bi-Flex Products
[Don't confuse this supplement with glutamine]
Joint pain and joint diseases are the most frequent causes of pain and disability. Glucosamine, an amino sugar, is thought to promote the formation of cartilage (glycosaminoglycans) and repair of cartilage. Chondroitin, a carbohydrate, is a cartilage component that is believed to promote water retention and elasticity and to inhibit enzymes that break down cartilage. Both compounds are produced by the human body. Glucosamine has been studied for many years with conflicting results. Further research needs to be done to identify specific characteristics in patients that produce positive results. Glucosamine comes in two forms: Glucosamine Hydrochloride and Glucosamine Sulfate. Chondroitin Sulfate is also combined in many products. There are studies that show that conclude that these products are not effective and there are studies that show that these products are effective. There are also some studies that conclude that the sulfate form is more effective; and others that the HCL form is more effective.

Amazingly, a search of the National Library of Medicine on PubMed.gov does not find any research regarding runners or athletic situations and knee pain and glucosamine. The research attention is toward older adults with osteoarthritis. There is a need for research on younger adults and athletes. There is also a need for research to determine if older adults have more irreversible situations regarding cartilage damage in which glucosamine can no longer provide effective results.

Side Effects or Interactions
to Ask Your Doctor About?

Diabetics beware. Possible increase in insulin resistance.

Shellfish allergic reactions (very rare).

Excess sodium in some products.

Mild reversible gastrointestinal side effects.

Resources to search for information on your own:
American College of Rheumatology
ConsumerLab.com
QuackWatch.com
PubMed.gov

DON'T TREAT MEDICAL CONDITIONS ON YOUR OWN. ALWAYS SEEK PHYSICIAN ADVICE AND TREATMENT.

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*Some products may not be appropriate for certain individuals. Always check with your physician before starting an exercise program. Not all products have been reviewed by the personal training staff at CoolFitnessGifts.com. Products that have proven themselves in the gym or in the field are indicated in the product detail.

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BAROMETRIC CHANGE AND COOLER TEMPERATURES DO AFFECT JOINT PAIN
By merging data collected from an Online Glucosamine Trial (a large scale study of an over-the-counter arthritis treatment) with NOAA data, researchers were able to compare the influence of changes in barometric pressure and surrounding air temperature on patients with knee arthritis.

The Online Glucosamine Trial, included 41 states between 2000 and 2002, tracked 205 arthritis patients, average age 60.2 years, in three-month online randomized controlled trials. Later researchers began to consider weather as an issue. and identified the nearest weather station by zip code for each of participant. They studied temperature, barometric pressure, precipitation and dew point specific to each participant's location. Average values were computed over one, three and seven days prior to each participant's report of pain. The change in each measure in the 24 hours prior to pain reports was also studied. The results showed changes in barometric pressure have a very strong association with increases in knee pain. Cooler temperatures were also consistently, but not as strongly, associated with increased pain. No significant associations were found with dew point or precipitation. Increased barometric pressure was associated with less pain.

The research was presented at the 2004 American College of Rheumatology Annual Scientific Meeting in San Antonio, Texas (Presentation Number: 596 -- Barometric Pressure and Ambient Temperature Influence Osteoarthritis (OA) Pain. Results of A National Web-Based Prospective Study. Timothy E. McAlindon, Margaret K. Formica, Jeremiah Fletcher, Chris Schmid. Tufts - New England Medical Center, Boston, MA).

 


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